MASCC guidelines on the prevention and management of acute radiation dermatitis

28 June 2023 - Research -

Acute radiation dermatitis (ARD) is a common complication in cancer patients undergoing radiation therapy.

A systematic review of the latest research on the prevention and management of acute radiation dermatitis (ARD) entitled "MASCC clinical practice guidelines for the prevention and management of acute radiation dermatitis: part 1) systematic review" was recently published".
The study was conducted by the Oncodermatology study group of MASCC (Multinational Association Of Supportive Care In Cancer), an international, non-profit and multidisciplinary organisation dedicated to research and education of supportive care for oncological patients.

The authors conducted a comprehensive search of multiple databases and included randomised and nonrandomised studies that met the inclusion criteria. 5173 articles published between 1946 and January 2023 were reviewed, of which 235 were selected for analysis.

Role of laser therapy

Photobiomodulation therapy (PBMT) emerged as one of the most promising treatments. The authors found that PBMT was more efficient in the prevention of ARD compared to standard care and/or placebo, particularly in patients with breast cancer.

Of the 5 randomised studies on PBMT that were selected and analysed in the review, 2 were conducted by Dr Robijin's group using the M6 robotic laser device, from the MLS^® family.

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Lasers in Surgery and Medicine - Journal

Prevention of Acute Radiodermatitis by Photobiomodulation: A Randomized, Placebo-Controlled Trial in Breast Cancer Patients (TRANSDERMIS Trial)
J. Robijns, S. Censabella, S. Claes, L. Pannekoeke, L. Bussé, D. Colson, I. Kaminski, P. Bulens, A. Maes, L. Noé, M. Brosens, A. Timmermans, I. Lambrichts, V. Somers, J. Mebis
Lasers in Surgery and Medicine, 9999:1-9 (2018)

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Biophysical skin measurements to evaluate the effectiveness of photobiomodulation therapy in the prevention of acute radiation dermatitis in breast cancer patients
J. Robijns, S. Censabella, S. Claes, L. Pannekoeke, L. Bussé, D. Colson, I. Kaminski, J. Lodewijckx, P. Bulens, A. Maes, L. Noé, M. Brosens, A. Timmermans, I. Lambrichts, V. Somers, J. Mebis
Support Care Cancer, 2018

What are the future prospects?

The quality of studies on the application of MLS^® Laser Therapy in the prevention of ARD in breast cancer patients was considered good and potentially opens the door to future applications.
It is important to underline that in general the scientific evidence in this area is still limited and that the use of laser therapy in cancer patients is still under observation and the subject of multiple studies.

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