Application of Concentrated Growth Factors (CGF) and Mphi Laser to Treat Defects in the Oral and Maxillofacial Region. A two - case report.

N. Doan, L. Nguyen-Pham, C. Liang, Q. T. Duong
Energy for Health [16], 2017

The application of Concentrated Growth Factors (CGF) in oral and maxillofacial surgery (OMS) and, in general, in regenerative medicine is steadily increasing. The purpose of this study is to present a review and case reporting on the use of CGF for tissue regeneration in the oral maxillofacial region.
Literature search was carried out using Medline search and manual search using the keywords: “concentrated”, “growth factors”, “tissue engineering”, “regenerative medicine” and “blood”. The review followed the method recommended by PRISMA and included clinical studies with adequate information. Papers with lack of data were excluded. Additionally, authors’ experience on this topic was reported with the description of two relevant cases. In both patients, bony defects were filled with autologous fibrin rich CGF and synthetic alloplastic materials, and then treated with Mphi laser.
Results: There were no published data on the combined use of Mphi laser and CG Fin clinical applications in the OMS region. Two case reports on the surgical regenerative management of oral lesions CGF and Mphi laser were described. Postoperative recovery was uneventful. Laser was effective in reducing postoperative pain, swelling, bleeding, speech impairment, analgesic use, trismus and wound healing. There was no difference in wound healing after one and 3 months.
Conclusion: The innovative application of Concentrated Growth Factors (CGF) in combination with Mphi laser in Oral and Maxillofacial Region defectsproduced rapid improvement and minimized complications. The treatment is fairly simple and cost effective.